{ "_id": "6a212c0ccd65a98ecbd23722", "Package": "SimNPH", "Type": "Package", "Title": "Simulate Non-Proportional Hazards", "Version": "0.5.8", "Authors@R": "c(person(\"Tobias\", \"Fellinger\", email=\"tobias.fellinger@ages.at\", role=c(\"aut\", \"cre\"), comment = c(ORCID = \"0000-0001-9474-2731\")),\nperson(\"Florian\", \"Klinglmueller\", role=c(\"aut\"), comment = c(ORCID = \"0000-0002-7346-3669\")))", "License": "BSL-1.0", "Description": "A toolkit for simulation studies concerning time-to-event\nendpoints with non-proportional hazards. 'SimNPH' encompasses\nfunctions for simulating time-to-event data in various\nscenarios, simulating different trial designs like\nfixed-followup, event-driven, and group sequential designs. The\npackage provides functions to calculate the true values of\ncommon summary statistics for the implemented scenarios and\noffers common analysis methods for time-to-event data. Helper\nfunctions for running simulations with the 'SimDesign' package\nand for aggregating and presenting the results are also\nincluded. Results of the conducted simulation study are\navailable in the paper: \"A Comparison of Statistical Methods\nfor Time-To-Event Analyses in Randomized Controlled Trials\nUnder Non-Proportional Hazards\", Klinglmüller et al. (2025)\n.", "Encoding": "UTF-8", "LazyData": "true", "Config/testthat/edition": "3", "VignetteBuilder": "knitr", "RoxygenNote": "7.3.3", "Roxygen": "list(markdown = TRUE)", "URL": "https://simnph.github.io/SimNPH/,\nhttps://github.com/SimNPH/SimNPH/", "BugReports": "https://github.com/SimNPH/SimNPH/issues/", "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libx11-dev", "Repository": "https://simnph.r-universe.dev", "Date/Publication": "2025-09-19 09:05:32 UTC", "RemoteUrl": "https://github.com/simnph/simnph", "RemoteRef": "HEAD", "RemoteSha": "e16f166bf530a912f4f7eb3e9adef106c56a3785", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-04 07:36:51 UTC", "User": "root" }, "Author": "Tobias Fellinger [aut, cre] (ORCID:\n),\nFlorian Klinglmueller [aut] (ORCID:\n)", "Maintainer": "Tobias Fellinger ", "MD5sum": "8ea69a7df9f685e6816df1117e54fd0c", "_user": "simnph", "_type": "src", "_file": "SimNPH_0.5.8.tar.gz", "_fileid": 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biostatistician ans statistical programmer currently working at the Austrian Medicines and Medical Devices Agency.\n\nI mainly code in R.", "uuid": 103025608, "orcid": "0000-0001-9474-2731" }, "_registered": true, "_dependencies": [ { "package": "SimDesign", "role": "Depends" }, { "package": "survival", "role": "Depends" }, { "package": "R", "version": ">= 4.1.0", "role": "Depends" }, { "package": "miniPCH", "version": ">= 0.3.0", "role": "Imports" }, { "package": "purrr", "version": ">= 1.0.0", "role": "Imports" }, { "package": "rlang", "role": "Imports" }, { "package": "tibble", "role": "Imports" }, { "package": "nph", "role": "Imports" }, { "package": "nphRCT", "role": "Imports" }, { "package": "car", "role": "Imports" }, { "package": "dplyr", "role": "Imports" }, { "package": "stringr", "role": "Imports" }, { "package": "methods", "role": "Imports" }, { "package": "tidyr", "role": "Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" 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"topics": [ "design_group_sequential" ] }, { "page": "generate_crossing_hazards", "title": "Generate Dataset with crossing hazards", "topics": [ "assumptions_crossing_hazards", "cen_rate_from_cen_prop_crossing_hazards", "generate_crossing_hazards", "hr_after_crossing_from_PH_effect_size", "true_summary_statistics_crossing_hazards" ] }, { "page": "generate_delayed_effect", "title": "Generate Dataset with delayed effect", "topics": [ "assumptions_delayed_effect", "cen_rate_from_cen_prop_delayed_effect", "generate_delayed_effect", "hr_after_onset_from_PH_effect_size", "true_summary_statistics_delayed_effect" ] }, { "page": "generate_subgroup", "title": "Generate Dataset with different treatment effect in subgroup", "topics": [ "assumptions_subgroup", "cen_rate_from_cen_prop_subgroup", "generate_subgroup", "hazard_subgroup_from_PH_effect_size", "true_summary_statistics_subgroup" ] }, { "page": "labs_from_labels", "title": "Add ggplot axis labels from labels attribute", "topics": [ 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